Udo Bartsch Selected Research

Cathepsin B

10/2021	Analysis of cathepsin B and cathepsin L treatment to clear toxic lysosomal protein aggregates in neuronal ceroid lipofuscinosis.
1/2020	Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis.

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Udo Bartsch Research Topics

Disease

10	Retinal Degeneration 10/2023 - 05/2011
9	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 10/2023 - 10/2013
4	Gliosis 10/2021 - 03/2016
3	Retinal Dystrophies 01/2022 - 01/2021
2	Ganglion Cysts (Ganglion) 11/2021 - 09/2014
2	Neuroinflammatory Diseases 01/2019 - 05/2014
2	Infections 10/2018 - 02/2015
2	Fasciculation (Fasciculations) 01/2003 - 10/2002
1	Panuveitis 07/2023
1	Disease Progression 07/2023
1	Hypertrophy 01/2022
1	Protein Deficiency 01/2022
1	Optic Nerve Diseases (Optic Neuropathy) 11/2021
1	Weight Loss (Weight Reduction) 10/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2021
1	Blindness (Hysterical Blindness) 01/2020
1	Glaucoma 11/2018
1	Mucopolysaccharidoses 03/2016
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 02/2015
1	neuronal 5 Ceroid lipofuscinosis 01/2015
1	Hypoxia (Hypoxemia) 11/2014
1	Retinopathy of Prematurity (Retrolental Fibroplasia) 11/2014
1	Vascular Remodeling 11/2014
1	Retinal Neovascularization 11/2014
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 05/2014
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 12/2013
1	Glioma (Gliomas) 11/2013
1	Glioblastoma (Glioblastoma Multiforme) 11/2013
1	Neoplasms (Cancer) 11/2013
1	Hereditary Corneal Dystrophies 02/2007
1	Optic Nerve Injuries 03/2003

Drug/Important Bio-Agent (IBA)

7	Retinaldehyde (Retinal)IBA 10/2023 - 05/2011
4	EnzymesIBA 01/2022 - 03/2016
4	lysosomal proteinsIBA 01/2021 - 10/2013
3	Cathepsin DIBA 01/2022 - 01/2020
3	Ciliary Neurotrophic Factor (CNTF)IBA 01/2015 - 12/2013
2	cerliponase alfaIBA 10/2023 - 01/2019
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2022 - 01/2020
2	Nerve Growth Factors (Neurotrophins)IBA 11/2021 - 01/2015
2	SaposinsIBA 10/2021 - 01/2020
2	Protein AggregatesIBA 10/2021 - 01/2020
2	Cathepsin BIBA 10/2021 - 01/2020
2	Proteins (Proteins, Gene)FDA Link 10/2021 - 01/2020
2	Cathepsin LIBA 10/2021 - 01/2020
2	Glial Fibrillary Acidic ProteinIBA 01/2020 - 10/2013
2	CeroidIBA 01/2020 - 05/2014
1	Peptide Hydrolases (Proteases)FDA Link 10/2021
1	Aspartic Acid ProteasesIBA 01/2021
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020
1	procathepsin DIBA 01/2020
1	oxidized low density lipoproteinIBA 01/2020
1	Tripeptidyl-Peptidase 1IBA 01/2020
1	Adenosine Triphosphate (ATP)IBA 01/2020
1	BuffersIBA 01/2020
1	LipofuscinIBA 01/2020
1	Lysergic Acid Diethylamide (LSD)IBA 01/2020
1	Mannose (D-Mannose)IBA 01/2020
1	Phosphates (Orthophosphate)IBA 01/2020
1	LDL Receptors (LDL Receptor)IBA 01/2020
1	Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)IBA 01/2020
1	Lysosomal-Associated Membrane Protein 1IBA 01/2020
1	Lysosomal-Associated Membrane Protein 2IBA 01/2020
1	palmitoyl-protein thioesteraseIBA 10/2019
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2019
1	Testosterone (Sustanon)FDA Link 10/2018
1	Lysosomal Membrane ProteinsIBA 09/2016
1	GlycosaminoglycansIBA 03/2016
1	ArylsulfatasesIBA 03/2016
1	Prion ProteinsIBA 02/2015
1	Metalloproteases (Metalloproteinases)IBA 02/2015
1	PrionsIBA 02/2015
1	Neuroprotective AgentsIBA 01/2015
1	Oxygen (Dioxygen)IBA 11/2014
1	CEACAM1 ProteinIBA 11/2014
1	lipopigmentsIBA 05/2014
1	Membrane Proteins (Integral Membrane Proteins)IBA 05/2014
1	ProlactinIBA 11/2013
1	Prolactin Receptors (Prolactin Receptor)IBA 11/2013
1	IntegrinsIBA 11/2013
1	Complementary DNA (cDNA)IBA 11/2013
1	Angiogenesis InhibitorsIBA 11/2013
1	type IV collagen alpha3 chain (Goodpasture antigen)IBA 11/2013
1	EndostatinsIBA 11/2013
1	Rhodopsin (Visual Purple)IBA 10/2013
1	OsteopontinIBA 05/2011
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 05/2011
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 03/2003
1	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 01/2003
1	Immunoglobulins (Immunoglobulin)IBA 01/2003
1	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 10/2002

Therapy/Procedure

6	Therapeutics 10/2023 - 02/2007
3	Enzyme Replacement Therapy 10/2023 - 01/2020
1	Duration of Therapy 07/2023
1	Transplantation 11/2021
1	Contact Lenses 02/2007